Metaphors are essential to writing about science. Even scientists themselves use metaphors all the time, drawing from their familiar experiences to describe the unfamiliar. Building proteins is known as translation, for example, because the sequences of DNA and proteins are akin to words written in different languages. The cell has to translate one language into another using–another metaphor–the genetic code.

Metaphors can be powerful, but they can also trip us up if we mistake them for an equivalence. DNA isn’t really a human language, for example. In my latest column for Discover, I take a look at another tricky metaphor: the eye as camera. Some scientists are actually making that metaphor real, by building video cameras that can let blind people see. As I point out, however, eyes are not cameras, and the differences are fascinating. They’re also crucial to the future success in treating blindness with technology. Check it out.

Originally published September 16, 2011. Copyright 2011 Carl Zimmer.

Discover, September 15, 2011

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For 100 million people around the globe who suffer from macular degeneration and other diseases of the retina, life is a steady march from light into darkness. The intricate layers of neurons at the backs of their eyes gradually degrade and lose the ability to snatch photons and translate them into electric signals that are sent to the brain. Vision steadily blurs or narrows, and for some, the world fades to black. Until recently some types of retinal degeneration seemed as inevitable as the wrinkling of skin or the graying of hair—only far more terrifying and debilitating. But recent studies offer hope that eventually the darkness may be lifted.

Continue reading ““I See,” Said the Blind Man With an Artificial Retina”

After a fairly quiet summer, I’m going to be giving some talks this fall, starting around my neighborhood and then radiating outwards. Here’s a preliminary list of public events. I may be adding extra ones as the launch of Science Ink approaches. You can find the most up-to-date information on my talks page.

Continue reading “Autumn yammerings: Where I’ll be talking this fall”

In tomorrow’s New York Times, I have a profile of Arthur Horwich, a medical geneticist who has spent a quarter century trying to figure out the workings of this beautiful molecular box. Today he won the Lasker Award, a prize for medicine that has often gone to scientists who later won the Nobel. Why all accolades for a little box? Because without it, you’d be dead. And as Horwich and others have discovered what goes on inside, they’ve helped change the way we understand the biology of the cell. Check it out.

[Image of GroEL from Molecular Chaperone Group, Birkbeck College]