On the last day of December, I turned in the final draft of my book about E. coli and the meaning of life. This is the sixth time around for me, and I’m getting familiar now with the havoc the experience wreaks on my nerves. In the final few weeks, the book becomes a monster that follows me around to every room of the house, out on the walks I take with my family. It crouches in the movie theaters and restaurants where I go with my wife to take a break. It just sits there, rumbling and wheezing, making me aware that it is still with me. I work late into the night, trying to get it out of the house and out of my life.

Continue reading “The Beast Takes a Break” →

One reason I love writing about biology is that it has so many levels. Down at the molecular scale, proteins flop and twist. Higher up, cells crawl and feed and divide. They organize into animals and plants and other big organisms, which must obey their own rules in order to survive. For some organisms, a day is a lifetime. Others must weather centuries. When millions of organisms get together, they form ecosystems that wax and wane in ways that could not be predicted from lower levels. And over the course of generations, genes take on a new personality, no longer passive bits of code, but units of selection that can sweep across the planet and leap from species to species.

Continue reading “Up and Down Life’s Staircase” →

PLOS Computational Biology, December 29, 2006

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The Buddha once told a story about a king who ordered a group of blind men to be presented with an elephant. Each man touched a different part of the animal. The king then asked them what an elephant is like.

The blind men who touched the elephant’s head replied, “An elephant, your majesty, is just like a water jar.” The blind men who touched its ear said, “An elephant, your majesty, is just like a winnowing basket.” The blind men who touched its tusk declared, “An elephant, your majesty, is just like a plowshare.” The ones who touched the trunk replied, “An elephant, your majesty, is just like a plow pole.”

Continue reading “The Genome: An Outsider’s View” →

Fellow science blogger Coturnix is assembling some posts about science for an anthology. He’s been asking for people to contribute suggestions. I’ve been meaning to thumb through my old posts in order to send one over, but it’s been more of a challenge than I thought. Part of the problem is that pieces of writing are like children, and it’s no fun to break up the family. The other part of the problem is that my brain is just about reduced to goo between finishing my book and managing a couple of sick kids over the Christmas break.

Continue reading “An Appeal to the Loom’s Collective Hive Wisdom: Help Me Pick a Post” →

The New York Times, December 27, 2006

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NEW YORK — NEW YORK: If you happen across a pond full of croaking green frogs, listen carefully. Some of them may be lying.

A croak is how male green frogs tell other frogs how big they are.

The bigger the male, the deeper the croak. The sound of a big male is enough to scare off other males from challenging him for his territory.

While most croaks are honest, some are not. Some small males lower their voices to make themselves sound bigger. Their big-bodied croaks intimidate frogs that would beat them in a fair fight.

Continue reading “In the fight for survival, it can help to bluff” →