A lot of people are reading scientific papers for the first time these days, hoping to make sense of the coronavirus pandemic. If you’re one of them, be advised the scientific paper is a peculiar literary genre that can take some getting used to. And also bear in mind that these are not typical times for scientific publishing.

It is hard to think of another moment in history when so many scientists turned their attention to one subject with such speed. In mid-January, scientific papers began trickling out with the first details about the new coronavirus. By the end of the month, the journal Nature marveled that over 50 papers had been published.

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The New York Times, May 27, 2020

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The first confirmed coronavirus infections in Europe and the United States, discovered in January, did not ignite the epidemics that followed, according to a close analysis of hundreds of viral genomes.

Instead, the outbreaks plaguing much of the West began weeks later, the study concluded. The revised timeline may clarify nagging ambiguities about the arrival of the pandemic.

For example, while President Trump has frequently claimed that a ban on travelers from China prevented the epidemic from becoming much worse, the new data suggest that the virus that started Washington State’s epidemic arrived roughly two weeks after the ban was imposed on Feb. 2.

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The New York Times, May 20, 2020 (with Knvul Sheikh and Noah Weiland)

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In a medical research project nearly unrivaled in its ambition and scope, volunteers worldwide are rolling up their sleeves to receive experimental vaccines against the coronavirus — only months after the virus was identified.

Companies like Inovio and Pfizer have begun early tests of candidates in people to determine whether their vaccines are safe. Researchers at the University of Oxford in England are testing vaccines in human subjects, too, and say they could have one ready for emergency use as soon as September.

Moderna on Monday announced encouraging results of a safety trial of its vaccine in eight volunteers. There were no published data, but the news alone kindled hopes and sent the company’s stock soaring.

Continue reading “A New Entry in the Race for a Coronavirus Vaccine: Hope” →

A prototype vaccine has protected monkeys from the coronavirus, researchers reported on Wednesday, a finding that offers new hope for effective human vaccines.

Scientists are already testing coronavirus vaccines in people, but the initial trials are designed to determine safety, not how well a vaccine works. The research published Wednesday offers insight into what a vaccine must do to be effective and how to measure that.

“To me, this is convincing that a vaccine is possible,” said Dr. Nelson Michael, the director of the Center for Infectious Diseases Research at Walter Reed Army Institute of Research.

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