A Request For The Hive Mind: Did Darwin Write About Microbes?

Posted on by Lori Jia

Having just written a book all about E. coli, including its evolution, I came to wonder what Darwin thought about microbes. I’ve searched far and wide. I’ve looked in biographies, for example, and the awesome site Darwin Online. I have found only one reference–to viruses:

A particle of small-pox matter, so minute as to be borne by the wind, must multiply itself many thousandfold in a person thus inoculated; and so with the contagious matter of scarlet fever. 

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Distinguishing Artificial From Natural Is Possible, for Now

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WIRED, March 21, 2008

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We like to tell ourselves that it’s easy to distinguish between the natural and the artificial, but they have a knack for fooling us. When European colonists traveled through the patchwork of forests and meadows of New England, they thought they were exploring primeval nature. In fact, Native Americans had been tending it carefully with fires for centuries. When the Viking probe snapped a fuzzy picture of a mountain on Mars in 1976, some people were sure it showed a giant face carved by Martians. When another probe took a sharper picture in 2001, all trace of the face had vanished.

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Spinach, Lettuce, and the Limits of Bioterrorism

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Slate, March 19, 2008

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An outbreak of E. coli isn’t usually the stuff of feel-good stories. Feel-bad is more like it–or even feel-organ-failure. But recent E. coli outbreaks can offer us a bit of solace. We live in the anxious age of synthetic biology, when scientists can reconstruct entire genomes from raw chemicals, and when we all fret that someone is going to use this new technology to create a monster bug and unleash a man-made plague. According to one government report, “The effects of some of these engineered biological agents could be worse than any disease known to man.” But a close look at recent outbreaks of E. coli–and a closer look at the bacteria themselves–may help us to put aside our fears for the moment. Engineering plagues is harder than it looks.

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E. coli, Nastier Than Ever, Cause for Comfort?

Posted on by Lori Jia

Well, we’re down now to seven weeks till Microcosm hits the book stores. Here and elsewhere I’m going to discuss some of the fascinating things I discovered about E. coli–and life in general–while working on the book. For instance, I came to have a grudging respect for the vicious strain of E. coli known as O157:H7, which has caused outbreaks in recent years in contaminated foods. The weaponry it uses to attack and subvert our cells is quite impressive. But my respect went up a notch more when scientists recently reported how E. coli O157:H7 has been continuing to evolve into an even nastier bug. Over at Slate today, I explain why there’s a silver lining in this microbial cloud–it means we should be a bit skeptical that anyone is going to engineer a killer bug from scratch any time soon.

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