The New York Times, March 21, 2011

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Ever since Darwin, biologists have recognized that life evolves. But in the past 25 years, some researchers have argued that certain organisms are better at evolving than others. Their genomes have a flexibility that lets them adapt effectively. The less evolvable species, by contrast, are too rigid to take advantage of new mutations or to find new solutions for survival.

Many biologists agree that evolvability makes sense in theory. But finding evidence of it in the natural world has proved difficult.

Continue reading “Tortoise and Hare, in a Laboratory Flask”

Earlier this month I was invited to deliver a keynote address at the Joint Summit on Translational Science in San Francisco. The meeting brings together scientists who seek to master the rising tide of biological data, in order to find new medical treatments. I urged them to think like ecologists, and treat the human body like an ecosystem of thousands of species.

I recorded my talk on my trusty iPhone, and I’ve posted the audio below. (You can download it.) It’s also here.

Continue reading “Dive into your inner lake: My keynote lecture on the microbiome (slides and audio)”

Charles Darwin pictured evolution as a grand tree, with the world’s living species as its twigs. Scientists identify 10,000 new species a year, but they’ve got a long, long way to go before finding all of Earth’s biodiversity. So far, they have identified 1.5 million species of animals, but there may be 7 million or more in total. Beyond the animal kingdom, our ignorance balloons. Scoop up some sea water or a cup of soil, and there will likely be thousands of new species of microbes lurking there. Fortunately, a lot of the species that scientists discover each year are fairly close relatives to species we already know about. There may be plenty of beetle species left to be discovered, for example, but they will all end up as tufts sprouting from the same beetle branch.

Continue reading “Glimpses of the Fourth Domain?”

Last year I wrote about how Craig Venter and his colleagues had inscribed a passage from James Joyce into the genome of a synthetic microbe. The line, “To live, to err, to fall, to triumph, to recreate life out of life,” was certainly apropos, but it was also ironic, since it is now being defaced as Venter’s microbes multiply and mutate.

Turns out there’s an even weirder twist on this story. Reporting from SXSW, David Ewalt writes about a talk Venter just gave. Venter recounted how, after the news of the synthetic microbe hit, he got a cease-and-desist letter from the Joyce estate. Apparently, the estate claimed he should have asked permission before copying the language. Venter claimed fair use.

Continue reading “Copyright law meets synthetic life meets James Joyce”

Last week I wrote in the New York Times about a fascinating new paper in which scientists described a lamp shell embryo that is, in effect, a swimming eyeball. The paper itself, however, comes in two parts. Along with the part on the swimming eyeball, the scientists also described a later stage of the lamp shell embryo in which it developed simple eyes connected to neurons. Its primitive version of our own eyes that reveals some interesting things about evolution–particularly about the different photoreceptors that evolved over half a billion years ago for sensing light. At the time, I was struck by the fact that this one paper had two newsworthy insights. So I was glad to see PZ Myer takes up the other half of the story in excellent detail over at Pharyngula. Check it out.

Originally published March 15, 2011. Copyright 2011 Carl Zimmer.