Jonathan Kurtz writes, “I started graduate school four years ago, studying the immune responses to chronic Salmonella infection in mice, similar to typhoid fever in humans.

“My project developed into defining how infections are combated in different anatomical locations and the host/microbial factors dictate these responses. I am scheduled to do my post-graduate studies with a collaborator of ours, so that I may stay in the Salmonella field, studying what is now a lifetime love/interest/career.

Continue reading “Today’s Microbiology Class Will Be At the Tattoo Parlor (Science Ink Sunday)” →

In the mid-1990s, people in the United States and Canada began to notice something grotesque. The frogs in their local ponds were sprouting extra legs.

As news of the deformed frogs spread, the Minnesota state government set up a hot line for sightings, and soon they got hundreds of calls from 54 out of 87 counties. “I’ve seen a lot of frogs over the years, and I’ve never seen anything like that,” a University of Minnesota herpetologist told the New York Times in 1996.

Continue reading “A Flurry of Frog Legs” →

Ten years ago, Jonathan Kipnis decided to run an experiment to see how well mice can learn new things. He suspected that the immune system was important to cognition, and so he wanted to compare mice with normal immune systems to mice with deficient ones. Kipnis engineered mice that lacked T cells, a type of white blood cell that fights pathogens. At the time, Kipnis was getting his Ph.D. at the Weizman Institute in Israel, and the lab he was working in didn’t have the equipment necessary for the test. So he shipped off his mice–a group of normal ones and a group lacking T cells–to Ben-Gurion University. There, his colleague Hagit Cohen put the mice through their paces.

Cohen gave the mice a task known as the Morris water maze. She put them in a pool of water, where they started to swim frantically. Just under the surface of the water there was a hidden stand. If the mice could find the stand, they could climb onto it and stop their desperate swimming. Over several rounds, the mice learned where the stand was hidden and swam straight for it.

Continue reading “Lifting Brain Fog” →

If you get rabies and don’t get help in time, you will almost certainly die. While there are a few tantalizing reports of people surviving a case of rabies without medical attention, there are all too many cases of people dying after getting bitten by a rabid animal. The virus sneaks from the bite wound into a nearby nerve and then makes its way through the nervous system. Along the way, it can make people mad and send them into comas before killing them. Officially, over 50,000 people die of rabies each year, but that number is likely a gross underestimate. A lot of rabies cases occur in places where the causes of deaths go unrecorded. In one study in Tanzania, doctors determined that the actual number of deaths from rabies was over 100 times higher than the official count.

Continue reading “To Stop Rabies, Stop Helping It” →

Brandon Klug writes, “I got this tattoo in January 2009 during the first year of my MSc research and it encompasses a lot of my scientific interests. My background is in zoology and I have a fascination with anatomy, specifically anything to do with the musculoskeletal system. When I got the tattoo, I was studying adaptations of reproductive and newborn tree-bats in Canada and very quickly became hooked on these amazing animals. One of the biggest puzzles in bat evolution was the question of whether they echolocated or flew first, and this fossil (Onychonycteris finneyi), the oldest bat fossil (52 million years old) yet discovered, led to the conclusion that bats evolved the ability to fly before they developed echolocation. In general, this tattoo represents my love for anatomy, evolution, and bats in general.”

By pure coincidence, I wrote about Onychonycteris finneyi when it was first unveiled in 2008. Here’s my Loom post.

You can see the rest of the Science Tattoo Emporium here and in Science Ink: Tattoos of the Science Obsessed.

Originally published February 10, 2013. Copyright 2013 Carl Zimmer.