The other day I used Post-it notes to organize my ideas for the last chapter of my book about heredity. On the one hand, getting to this point feels good: Last chapter! Lots of ideas! On the other hand, you readers probably won’t be happy with a pile of Post-it notes at the end of my book. So…I’m busy.

Since the last Friday’s Elk, I’ve published a couple columns for the New York Times. Recently, a group of scientists published a review about the emerging science of making embryo-like…things. They’re not eggs fertilized by sperm. They’re reprogrammed stem cells that, when combined with each other, start to develop embryo-like features. We can learn a lot from them. But how far should we let them go? Here’s my look at the ethics of this brave new world. Continue reading “Friday’s Elk, March 25, 2017”

The New York Times, March 21, 2017

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As biological research races forward, ethical quandaries are piling up. In a report published Tuesday in the journal eLife, researchers at Harvard Medical School said it was time to ponder a startling new prospect: synthetic embryos.

In recent years, scientists have moved beyond in vitro fertilization. They are starting to assemble stem cells that can organize themselves into embryolike structures.

Soon, experts predict, they will learn how to engineer these cells into new kinds of tissues and organs. Eventually, they may take on features of a mature human being.

Continue reading “A New Form of Stem-Cell Engineering Raises Ethical Questions”

The New York Times, March 8, 2017

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Human skeletons and archaeological remains in Australia can be traced back nearly 50,000 years before the trail disappears. Before then, apparently, Australia was free of humans.

So how did people get there, and when? Where did humans first arrive on the continent, and how did they spread across the entire landmass?

Answers to some of these questions are stored in the DNA of Aboriginal Australians. A genetic study of 111 Aboriginal Australians, published on Wednesday, offers an interesting — and, in some respects, unexpected — view of their remarkable story.

Continue reading “How Did Aboriginal Australians Arrive on the Continent? DNA Helps Solve a Mystery”

I’m writing to you from the lovely town of La Jolla, California, where I’m participating in Future of Genomic Medicine, a meeting where scientists are talking about how sequencing our DNA is going to affect our lives. I gave a talk yesterday about the experience of getting my genome sequenced. If you’re on Twitter, you can read about the presentations under the hashtag #FOGM17.

From here, I’m heading to Palo Alto. If you live anywhere near Stanford University, please consider joining me for a talk at 1 pm on Monday, March 6, in McCaw Hall. I’m giving the keynote address at the annual meeting of the Stanford Center for Computational, Evolutionary and Human Genomics. Details here. Continue reading “Friday’s Elk, March 3, 2017”

The New York Times, March 1, 2017

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They are microscopic artwork: tiny tubes and long filaments, strange squiggles etched into some of the most ancient rocks known.

On Wednesday, researchers reported that these may be the oldest fossils ever discovered, the remains of bacteria thriving on Earth not long, geologically speaking, after the very birth of the planet. If so, they offer evidence that life here got off to a very early start.

But many experts in the field were skeptical of the new study — or downright unconvinced.

Continue reading “Scientists Say Canadian Bacteria Fossils May Be Earth’s Oldest”