The New York Times, October 4, 2018

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People of Asian and European descent — almost anyone with origins outside of Africa — have inherited a sliver of DNA from some unusual ancestors: the Neanderthals.

These genes are the result of repeated interbreeding long ago between Neanderthals and modern humans. But why are those genes still there 40,000 years after Neanderthals became extinct?

As it turns out, some of them may protect humans against infections. In a study published on Thursday, scientists reported new evidence that modern humans encountered new viruses — including some related to influenza, herpes and H.I.V. — as they expanded out of Africa roughly 70,000 years ago.

Continue reading “Deep in Human DNA, a Gift From the Neanderthals”

The New York Times, September 28, 2018

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For a hungry fish in search of a meal, a jellyfish would seem to be a huge disappointment. These gelatinous animals are 95 percent water. As a result, a cup of live jellyfish provides just five calories — one-third the amount in a cup of celery.

It should come as no surprise, then, that marine biologists long ago dismissed jellyfish as an insignificant item on the ocean menu. Other animals rarely bothered eating them, the idea went, and so they represented a dead end in the ocean’s food web.

Continue reading “Who Wants to Eat a Gooey Jellyfish? Pretty Much Everyone in the Ocean.”

The New York Times, September 18, 2018

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You have a gene called PNMA6F. All people do, but no one knows the purpose of that gene or the protein it makes. And as it turns out, PNMA6F has a lot of company in that regard.

In a study published Tuesday in PLOS Biology, researchers at Northwestern University reported that of our 20,000 protein-coding genes, about 5,400 have never been the subject of a single dedicated paper.

Most of our other genes have been almost as badly neglected, the subjects of minor investigation at best. A tiny fraction — 2,000 of them — have hogged most of the attention, the focus of 90 percent of the scientific studies published in recent years.

Continue reading “Why Your DNA Is Still Uncharted Territory”

The New York Times, September 11, 2018

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How generous is an ape? It’s a hard question for scientists to tackle, but the answer could tell us a lot about ourselves.

People in every culture can be generous, whether they’re lending a cellphone to an office mate or sharing an antelope haunch with a hungry family.

While it’s easy to dwell on our capacity for war and violence, scientists see our generosity as a remarkable feature of our species. “One of the things that stands out about humans is how helpful we are,” said Christopher Krupenye, a primate behavior researcher at the University of St. Andrews in Scotland.

Continue reading “Seeking Human Generosity’s Origins in an Ape’s Gift to Another Ape”

Living Medicines

For a science writer, it’s always exciting to report on the dawn of a new kind of science.

In the 1990s, journalists furiously wrote about gene therapy, a treatment that medical researchers promised would cure hereditary diseases by injecting working genes into people’s cells.

At the same time, champions of the Human Genome Project also promised tremendous benefits to mapping all our DNA. Continue reading “Friday’s Elk, September 9, 2018”