Craig Venter has followed up on his announcement that he and his coworkers have assembled a virus from its genome sequence. Now there’s a paper available at the Proceeding of the National Academy of Science web site. A bleary-eyed late-night inspection suggests that this is not a flawless Xerox machine for viruses; the researchers had to cast away lots of misassembled versions. (Still, they were able to isolate a perfect sequence in just two weeks.) More interestingly, the authors talk a bit about how they can use this same method to cobble together chunks of much bigger genomes to make synthetic microbes. That’s when things will get really interesting.

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Two decades ago, a neuroscientist named Benjamin Libet published a classic experiment on conscious will. He had his subjects rest a finger on a button as they stared at a specially designed clock. It had only one hand, which swept through a revolution once every 2.5 seconds. Libet would ask his subjects to push the button at their own choosing. In some runs, he asked them to note the position of the clock hand when they actually pushed the button. In other runs they had to note its position when they first began to think about pushing it.

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