Scientific American, January 1, 2011
A single neuron sits in a petri dish, crackling in lonely contentment. From time to time, it spontaneously unleashes a wave of electric current that travels down its length. If you deliver pulses of electricity to one end of the cell, the neuron may respond with extra spikes of voltage. Bathe the neuron in various neurotransmitters, and you can alter the strength and timing of its electrical waves. On its own, in its dish, the neuron can’t do much. But join together 302 neurons, and they become a nervous system that can keep the worm Caenorhabditis elegans alive—sensing the animal’s surroundings, making decisions and issuing commands to the worm’s body. Join together 100 billion neurons—with 100 trillion connections—and you have yourself a human brain, capable of much, much more.