The ongoing controversy over experimental strains of bird flu is one of those multi-dimensional stories that you just can’t fit into one article. I’ve written about it at Slate and here at the Loom, and I can point elsewhere to no end of excellent stuff. Fellow Discover blogger Ed Yong has a sharp, concise round-up on the research over at Nature, for example, and Michael Specter has a new story on it in this week’s New Yorker (subscription required, alas).

In tomorrow’s New York Times, I take a look into one dimension of the story that has seemed under-explored to me. The controversy over the bird flu revolves around the risk that publishing the full details of the research could lead someone to recreate the virus and unleash a pandemic. Not just a terrorist or a hostile nation, but perhaps even a so-called “garage scientist” toiling at home. Is this a realistic risk, or unfounded fear? After talking to virologists who make viruses for a living and DIY biologists who don’t, I find that the answer is pretty complicated. Check it out.

[Flue virus image: ESRF]

Originally published March 5, 2012. Copyright 2012 Carl Zimmer.

Discover, March 5, 2012

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Eric Courchesne managed to find a positive thing about getting polio: It gave him a clear idea of what he would do when he grew up. Courchesne was stricken in 1953, when he was 4. The infection left his legs so wasted that he couldn’t stand or walk. “My mother had to carry me everywhere,” he says. His parents helped him learn how to move his toes again. They took him to a pool to learn to swim. When he was 6, they took him to a doctor who gave him metal braces, and then they helped him learn to hobble around on them. Doctors performed half a dozen surgeries on his legs, grafting muscles to give him more strength.

Continue reading “The Troublesome Bloom of Autism”

The New York Times, March 5, 2012

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Just how easy is it to make a deadly virus?

This disturbing question has been on the minds of many scientists recently, thanks to a pair of controversial experiments in which the H5N1 bird flu virus was transformed into mutant forms that spread among mammals.

After months of intense worldwide debate, a panel of scientists brought together by the World Health Organization recommended last week in favor of publishing the results. There is no word on exactly when those papers — withheld since last fall by the journals Nature and Science — will appear.

Continue reading “Amateurs Are New Fear in Creating Mutant Virus”