Discover, May 15, 2012

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Theodore Nash sees only a few dozen patients a year in his clinic at the National Institutes of Health in Bethesda, Maryland. That’s pretty small as medical practices go, but what his patients lack in number they make up for in the intensity of their symptoms. Some fall into comas. Some are paralyzed down one side of their body. Others can’t walk a straight line. Still others come to Nash partially blind, or with so much fluid in their brain that they need shunts implanted to relieve the pressure. Some lose the ability to speak; many fall into violent seizures.

Underneath this panoply of symptoms is the same cause, captured in the MRI scans that Nash takes of his patients’ brains.

Continue reading “Hidden Epidemic: 
Tapeworms Living Inside People’s Brains”

We’ve all heard about tapeworms getting into the intestines. That’s bad enough. But sometimes they can also end up in the brain. In my column in the latest issue of Discover, I write about neurocysticercosis, which is shockingly common in some parts of the world, causing an estimated five million cases of epilepsy. Yet neurocysticercosis experts consider the disease as a fairly easy one to wipe out. We have the tools to do it, but not the will. Check it out.

Originally published May 15, 2012. Copyright 2012 Carl Zimmer.

We’ve learned a lot about how the brain works from functional magnetic resonance images. I should clarify: we’ve learned a lot about the human brain. Thousands of people have volunteered to lie down inside fMRI scanners and have the activity in their brains monitored as they perform different kinds of mental tasks, or even just do nothing at all. We must resist the temptation to look at the pretty fMRI images and think they’re just photographs of the mind. They’re actually more like very complex, statistically worked-over graphs. But even with those caveats, there’s a lot to learn from them. But fMRI only works if you hold very, very still. Having been scanned myself for a story a few years back, I can vouch that this experience takes a lot of patience, and a high tolerance for loud buzzing noises and for narrow, confined spaces. Scientists have managed to take fMRI scans of monkeys and rats, but they’ve either been knocked out cold, or restrained so the images of their brains don’t blur. If you can persuade a gorilla to lie peacefully in the bore of a scanner for half an hour and look at pictures of bananas, do let us know.

Continue reading “Scanning man’s best friend”