Cancer may not seem to have much to do with evolution, but they’re actually intimately linked. Cancer cells evolve within tumors, becoming better at exploiting our bodies and resisting cancer drugs. We have evolved a number of adaptations to fight cancer–or at least to put it off until past our child-bearing years. The intersection of cancer and evolution has become so fruitful that there’s now a biennial international meeting on the subject. This year, the meeting organizers asked me to give a public lecture on cancer and evolution in San Francisco. My talk, “The Devil’s Tumor,” will take place on Friday, June 14, at 7 pm–followed by a performance by the one and only Baba Brinkman. Details here. I hope Bay Area folk can join us!

Originally published June 4, 2013. Copyright 2013 Carl Zimmer.

The New York Times, June 3, 2013

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One day in 1788, students at the Hunterian School of Medicine in London were opening a cadaver when they discovered something startling. The dead man’s anatomy was a mirror image of normal. His liver was on his left side instead of the right. His heart had beaten on his right side, not his left.

The students had never seen anything like it, and they rushed to find their teacher, the Scottish physician Matthew Baillie, who was just as stunned as they were. “It is so extraordinary as scarcely to have been seen by any of the most celebrated anatomists,” he later wrote.

Continue reading “Growing Left, Growing Right” →

Not long ago, a friend of mine asked me if I had heard of a condition called situs inversus. He had learned about it when his grandson had been born with his internal organs flipped–heart on the right, liver on the left, and so on. Despite that remarkable reversal, the boy was fine. His story got me curious about how the condition happens–and how our bodies, for the most part, figure out which side is which. The result is a story in tomorrow’s New York Times. Check it out.

Originally published June 3, 2013. Copyright 2013 Carl Zimmer.

The Atlantic, June 2013

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When Jeannie Peeper was born in 1958, there was only one thing amiss: her big toes were short and crooked. Doctors fitted her with toe braces and sent her home. Two months later, a bulbous swelling appeared on the back of Peeper’s head. Her parents didn’t know why: she hadn’t hit her head on the side of her crib; she didn’t have an infected scratch. After a few days, the swelling vanished as quickly as it had arrived.

When Peeper’s mother noticed that the baby couldn’t open her mouth as wide as her sisters and brothers, she took her to the first of various doctors, seeking an explanation for her seemingly random assortment of symptoms. Peeper was 4 when the Mayo Clinic confirmed a diagnosis: she had a disorder known as fibrodysplasia ossificans progressiva (FOP).

Continue reading “The Girl Who Turned to Bone” →

The New York Times, May 31, 2013

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The stories of scientists create new scientists. Alexander von Humboldt — the most famous naturalist of the early 19th century — chronicled his epic expeditions, between 1799 and 1804, in his “Personal Narrative of a Journey to the Equinoctial Regions of the New Continent.” When a nature-loving student at Cambridge named Charles Darwin read the book, it changed his life. He read passages aloud to his professors and learned Spanish so that he could follow in Humboldt’s footsteps.

Continue reading “Apes” →