Say the letters “H M” to a neuroscientist, and chances are he or she will nod knowingly. H.M. was a man who died in 2008. His full name was Henry Molaison, and a surgical procedure in the 1950s left him without much of his memory. Studies on his mind laid the groundwork for our understanding of memory today. In tomorrow’s issue of the Wall Street Journal, I review a remarkable biography of Molaison, written by MIT neuroscientist Suzanne Corkin, who studied him from their first meeting in 1962 till his death–and beyond. While it’s not a perfect, it is–pardon the pun–a memorable one.

Originally published June 14, 2013. Copyright 2013 Carl Zimmer.

The Wall Street Journal, June 14, 2013

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In 1962, a young graduate student at McGill University named Suzanne Corkin met a 35-year-old man named Henry Molaison. Molaison and his mother had come to Montreal from their home in Connecticut so that Ms. Corkin and her colleagues could run a week-long series of psychological tests on him. Molaison was a sweet, cooperative subject. Ms. Corkin and Molaison talked a lot that week, mostly about Molaison’s childhood. Beyond his early years, though, Molaison’s recollections faded away.

The reason was both simple and profound. As a child, Molaison had suffered from severe epilepsy. In 1953, a surgeon took the drastic step of removing the part of his brain that was believed to be the cause.

Continue reading “The Man Who Wasn’t There”

I arrived this afternoon in San Francisco, so that I can participate in an exceptional sort of meeting: the 2nd International Biannual Evolution and Cancer Conference. Friday night I’ll be giving a talk about some of the lessons we can learn about cancer from other animals (details at the end of this post), but for the most part, I’ll be on the receiving end, learning about the latest research at this fascinating crossroads.

Cancer is fundamentally an evolutionary disease, as I explained in a 2007 article for Scientific American. By which I mean that cancer is an inevitable menace to any multicellular organism, which has led the evolution of lots of anti-cancer defenses in our biology. But each time cancer emerges, it plays out in an evolutionary process, a natural selection happening within our own bodies. As new mutations arise, certain cancer cells fare better than others. Tumors evolve, as their cells gaining all sorts of abilities–such as attracting new blood vessels to feed their voracious appetites–that their ancestors didn’t have.

Continue reading “Putting the Brakes On Cancer’s Evolution”

We typically look at rubies and other gems as treasure, bling, or signs of matrimony. But they are also historians, telling us about what the Earth was like hundreds of millions of years ago. In today’s Matter column in the New York Times, I talk to geologists who treat jewels as archives of planetary history. Check it out.

Originally published June 13, 2013. Copyright 2013 Carl Zimmer.

The New York Times, June 13, 2013

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A jewelry store is an archive of the Earth. Every gem fixed to every ring or necklace was forged deep inside our planet, according to its own recipe of elements, temperature and pressure.

But it has taken a while for geologists to decode the cookbook for gems. Jade, for example, puzzled geologists for decades. “For a long time people looked at this crazy rock, and it didn’t make any sense,” said George Harlow, a geologist at the American Museum of Natural History. But thanks to the research of Dr. Harlow and other geologists, jade now has a back story: It formed in dying oceans.

Continue reading “In Glittering Gems, Reading Earth’s Story”