The Atlantic, December 2013

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On April 28, 2009, a box containing a newly isolated virus showed up at Doris Bucher’s lab. She and her colleagues at New York Medical College opened it up right away. Thousands, or perhaps millions, of lives might depend on what they did next.

The virus was a new kind of influenza, known as 2009 H1N1. It had abruptly started spreading across North America in the previous month, and was beginning to appear in countries around the world. Once scientists at the Centers for Disease Control and Prevention analyzed it, they realized that the vaccine already in production for the next flu season probably wouldn’t be effective against it. And because it was so new, people’s immune systems might also be unable to stop the virus, which meant that it could become a global outbreak—a pandemic.

Continue reading “The Quest to End the Flu”

Many hospitals and medical practices are shifting from paper to computers, as they convert to electronic medical records. While the technology has been touted mainly as a way to cut costs and improve medical care, it turns out it has an unexpected side benefit: scientists can probe electronic medical records to find hidden connections between genes and diseases. This week in my “Matter” column for the New York Times, I look at this new tool for exploring to our DNA.

Continue reading “Genetic Secrets in Our Medical Records: My New Column for the New York Times”

The New York Times, November 28, 2013

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The days of scrawled doctor’s notes are slowly coming to a close. In the United States, 93 percent of hospitals are now using at least some electronic medical records and 2.2 percent have given up paper records completely, according to the consulting firm HIMSS Analytics.

The federal government has been pushing for electronic medical records for a decade, arguing that they will improve health care and bring down costs. That is still a matter of debate. Critics charge that the system is hobbled by poorly designed software and that some hospitals are using electronic medical records to bill more for the same services.

Continue reading “Linking Genes to Diseases by Sifting Through Electronic Medical Records”

There was a time when the Laysan albatross might seem a perfect icon for the virtues of marriage. When naturalists visited the bird’s nesting grounds in the Pacific, they’d find males and females bonded in pairs for life. Each breeding season the pairs of birds would nuzzle their heads together and perform other adorable courtship rituals. After they mated, the female would lay an egg. Both the male and female would take turns sitting on the nest to incubate it, taking three week shifts. After the chick hatched they’d rear it together until the end of the breeding season. The birds would then fly out to sea in different directions, but they’d return the following year and start up their partnerships all over again. The albatrosses would repeat this behavior for life–which, in their case, can last for many decades.

Continue reading “Same-Sex Mothers: Letting Albatrosses Be Albatrosses”

A few weeks ago I went to my local drug story a got a flu vaccine. So far <knock on lab bench> I’ve had a pretty healthy flu season. But there’s a fair chance I may get the flu anyway this winter, because flu vaccine effectiveness is modest compared to vaccines for many other diseases. What’s more, I’ll need to head back next year to the store to get another shot. That’s because flu vaccines today are still based in some fundamental ways–in their production in chicken eggs and in the molecules they target on viruses–on World War II-era science.

I’ve written an article for the December issue of the Atlantican article for the December issue of the Atlantic about how we got into this strange situation, and how scientists are trying to bring our fight against flu into the twenty-first century. Check it out.

Continue reading “The Future of Fighting the Flu: My Feature in The Atlantic”