The New York Times, November 2, 2015

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A mysterious die-off of endangered antelopes last spring in Central Asia was even more extensive than originally thought, killing more than half of the entire species in less than a month, scientists have found.

“I’ve worked in wildlife disease all my life, and I thought I’d seen some pretty grim things,” Richard A. Kock, of the Royal Veterinary College in London, said in a telephone interview. “But this takes the biscuit.”

At a scientific meeting last week in Tashkent, Uzbekistan, Dr. Kock and his colleagues reported that they had narrowed down the possible culprits. 

Continue reading “More Than Half of Entire Species of Saigas Gone in Mysterious Die-Off”

Greetings–

On Saturday, I gave a plenary talk at the annual meeting of the National Society of Genetic Counselors. I described the fast rise of CRISPR and encouraged the audience to consider the ethical questions that may arise if we gain the ability to fix diseases or even enhance traits in embryos. Laura Hercher, a genetic counselor at Sarah Lawrence College, also gave a talk in the session. She focused on mitochondrial replacement therapy, which is sometimes wrongly described as producing “three-parent babies.” Continue reading “Friday’s Elk, October 30, 2015”

The New York Times, October 28, 2015

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Scores of leading scientists on Wednesday urged the creation of a major initiative to better understand the microbial communities critical to both human health and every ecosystem.

In two papers published simultaneously in the journals Science and Nature, the scientists called for a government-led effort akin to the Brain Initiative, a monumental multiyear project intended to develop new technologies to understand the human brain.

“This is the beginning of the shot to the moon,” said Jeffery F. Miller, the director of the California NanoSystems Institute at the University of California, Los Angeles, and a co-author of the Science paper. “There is so much to learn, and so many benefits of learning it.”

Continue reading “Scientists Urge National Initiative on Microbiomes”

The New York Times, October 26, 2015

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Researchers have long wondered how people settled the Americas, particularly the path they took to the new territory and the timing of their expansion. Until recently, archaeologists studying these questions were limited mostly to digging up skeletons and artifacts.

But now scientists have begun extracting DNA from human bones, and the findings are providing new glimpses at the history of the first Americans. On Monday, researchers at the University of Alaska and elsewhere published an important addition to the growing genetic archive.

Continue reading “DNA of Ancient Children Offers Clues on How People Settled the Americas”

Greetings–

There are few things more interesting than ancient human DNA and diseases (if you ask me). So the opportunity to write about both of them in one article was the highlight of my week.

Scientists who have been gathering DNA from Bronze Age skeletons wondered if they might have unknowingly scooped up some DNA from interesting pathogens. Turns out, they did. From 5,000-year-old skeletons, they extracted the DNA of Yersinia pestis, the cause of the plague. The discovery pushes back the plague 3,000 years, and allows us to see the stepwise evolution of the pathogen into its full-blown, flea-carried form. Continue reading “Friday’s Elk, October 23, 2015”