This month, scientists gathered at the National Academy of Sciences in Washington to talk about Crispr, a new method for editing genes. In the past couple of years, the technique has become so powerful and accessible that many experts are calling for limits on its potential uses — especially altering human embryos with changes that could be inherited by future generations.

Among the scientists describing recent advances was one of Crispr’s pioneers, George Church of Harvard Medical School. In the midst of his presentation, packed with the fine details of biochemistry and genetics, Dr. Church dropped a bombshell.

Continue reading “Editing of Pig DNA May Lead to More Organs for People” →

A team of scientists reported on Thursday that it had recovered the genome from a 4,500-year-old human skeleton in Ethiopia — the first time a complete assemblage of DNA has been retrieved from an ancient human in Africa.

The DNA of the Ethiopian fossil is strikingly different from that of living Africans. Writing in the journal Science, the researchers conclude that people from the Near East spread into Africa 3,000 years ago. In later generations, their DNA ended up scattered across the continent.

Continue reading “Scientists Recover First Genome of Ancient Human From Africa” →

In 1977, a University of Oxford statistician named Richard Peto pointed out a simple yet puzzling biological fact: We humans should have a lot more cancer than mice, but we don’t.

Dr. Peto’s argument was beguilingly simple. Every time a cell divides, there’s a small chance it will gain a mutation that speeds its growth. Cells that accumulate several of these mutations may become cancerous. The bigger an animal is, the more cells it has, and the longer an animal lives, the more times its cells divide. We humans undergo about 10,000 times as many cell divisions as mice — and thus should be far more likely to get cancer.

Continue reading “Elephants: Large, Long-Living and Less Prone to Cancer” →