The New York Times, November 16, 2015

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A tooth fossil discovered in a Siberian cave has yielded DNA from a vanished branch of the human tree, mysterious cousins called the Denisovans, scientists said Monday.

Their analysis pushes back the oldest known evidence for Denisovans by 60,000 years, suggesting that the species was able to thrive in harsh climates for thousands of generations. The results also suggest that the Denisovans may have bred with other ancient hominins, relatives of modern humans whom science has yet to discover.

Todd Disotell, a molecular anthropologist at New York University who was not involved in the new study, said the report added to growing evidence that our species kept company with many near relatives over the past million years.

Continue reading “In a Tooth, DNA From Some Very Old Cousins, the Denisovans”

Greetings–

On this Friday the 13th, I wish you only good luck and offer you the following diversions…

The DNA of a Million Veterans

–I’ve got a new story at STAT, about the next chapter in the history of genetics. Researchers are launching massive studies of huge numbers of people in order to link genes to diseases. One of the biggest is being run by the U.S. military. The Veterans Administration is gathering the DNA of a million veterans to study everything from diabetes to PTSD. I went inside the Million Veteran Program to get a first-hand look at this new way of exploring our genes. (Be sure to check out the video of the enormous operation!) Continue reading “Friday’s Elk, November 13, 2015”

The New York Times, November 12, 2015

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From sharks to giraffes, many of Earth’s biggest and most magnificent species are threatened with extinction. A new study of the fossil record indicates that once large vertebrates disappear, evolution cannot quickly restore them — for tens of millions of years, most animals remain small.

The study, published Thursday in Science, emerged from research carried out by Lauren Sallan, a paleontologist at the University of Pennsylvania.

Studying fish that lived during the Mississippian Period, from 359 million to 323 million years ago, she noticed that they were substantially smaller than their ancestors.

Continue reading “After a Mass Extinction, Only the Small Survive”

STAT, November 11, 2015

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“This is our brand new freezer,” Don Humphries said. “It holds 4 million vials.”

You’d think a freezer big enough to hold 4 million vials of blood would be easy to spot. But to my great embarrassment, I couldn’t see it.

Humphries and I were standing in a lab in the basement of the Veterans Affairs hospital in the Jamaica Plain neighborhood of Boston. He had led me through a labyrinth of windowless rooms, packed with robots handling tubes of blood donated from veterans, pipes roaring with coolant, and gorilla-sized tanks of liquid nitrogen, until he stopped next to a featureless wall.

Continue reading “Inside the drive to collect DNA from 1 million veterans and revolutionize medicine”