“Game of Genomes” is here!

For the past few months, I’ve been traveling through my genome with the guidance of a couple dozen scientists. On Monday, Stat published the first part of my narrative of the experience. You can read it here.

As part of the package, I’ve also set up a parallel web site for the scientific nuts and bolts. I’ve posted some of the analysis that researchers produced while poring over my genome. And you can find the raw data of my genome there, too (including files of variants, and the original, gigantic BAM file). I hope it will be of use to teachers who want to show students how to make sense of a genome. I will add more materials as the next two parts of the series are published.

This week I also talked about the experience a few times. Continue reading “Friday’s Elk, July 15, 2016”

Monday: Ask Me Anything!

I was so busy looking back at the week that was that I forgot to mention that, on Monday at 3 pm ET, I will be on Reddit for an AMA about my genome series.

I’ll be answering questions about what it’s like to look at your own genome, the future of genomes in medicine, the evolutionary clues hidden in our DNA, and whatever other questions you may have. Please join us. Continue reading “A Friday’s Elk P.S.! I’ll be on Reddit on Monday”

The New York Times, July 15, 2016

Link

A fecal transplant is exactly what it sounds like: To treat certain gut disorders, doctors transfer stool from a healthy donor to a sick patient.

Just a few years ago, only a few doctors turned to fecal transplants, typically as a last resort. But in randomized trials, the procedure has proved remarkably effective against potentially fatal infections of bacteria known as Clostridium difficile.

The evidence has overwhelmed any squeamishness that physicians might have felt. “We’re doing this treatment almost weekly,” said Dr. Harry Sokol, a gastroenterologist at Saint-Antoine Hospital AP-HP in Paris.

Continue reading “Fecal Transplants Can Be Life-Saving, but How?”

STAT, July 11, 2016

Link

Episode Nine: Ancient paths of Y and X

Delving into my genome, I learned a lot about how genetic variants influence my health, putting me at risk of some disorders and protecting me from others. But I also wanted to search inside my DNA for my history — my own ancestry, and that of our entire species.

I am hardly alone in my curiosity. Many people are sending their spit to testing companies so that they can learn about their origins.

Continue reading “Game Of Genomes: Season 3”

STAT, July 11, 2016

Link

Episode Six: A Jedi in the wastelands

On a recent trip to Boston, I had breakfast with a scientist named Manolis Kellis. He met me in the little dining room at my hotel, and we grabbed plates to load with food. Immediately, Kellis was enchanted by the waffle iron. He started pouring a waterfall of batter onto the hot metal and piled up a mound of waffles on his plate.

“You have to help me eat these,” Kellis announced when we sat down. He spoke with a vestige of an accent; he was born in Greece as Manolis Kamvysselis, and came to the United States in 1995 to go to MIT for college. He never left; today he’s a waffle-loving professor of computer science there.

Continue reading “Game Of Genomes: Season 2”