I’ve got a new column in Discover on a scientist tracing the links from our genes to our personality. Here’s how it starts:

Ahmad Hariri stands in a dim room at the Duke University Medical Center, watching his experiment unfold. There are five computer monitors spread out before him. On one screen, a giant eye jerks its gaze from one corner to another. On a second, three female faces project terror, only to vanish as three more female faces, this time devoid of emotion, pop up instead. A giant window above the monitors looks into a darkened room illuminated only by the curve of light from the interior of a powerful functional magnetic resonance imaging (fMRI) scanner. A Duke undergraduate—we’ll call him Ross—is lying in the tube of the scanner. He’s looking into his own monitor, where he can observe pictures as the apparatus tracks his eye movements and the blood oxygen levels in his brain.

Ross has just come to the end of an hour-long brain scanning session. One of Hariri’s graduate students, Yuliya Nikolova, speaks into a microphone. “Okay, we’re done,” she says. Ross emerges from the machine, pulls his sweater over his head, and signs off on his paperwork.

As he’s about to leave, he notices the image on the far-left computer screen: It looks like someone has sliced his head open and imprinted a grid of green lines on his brain. The researchers will follow those lines to figure out which parts of Ross’s brain became most active as he looked at the intense pictures of the women. He looks at the brain image, then looks at Hariri with a smile. “So, am I sane?”

Hariri laughs noncommitally. “Well, that I can’t tell you.”

True enough: On its own, Ross’s brain can’t tell Hariri much. But a thousand brains? That’s another matter. Hariri is in the midst of assembling a large cohort of Duke undergraduates and gathering key information—brain scans, psychological tests, and genetic markers—for the Duke Neurogenetics Study. From this mountain of data, Hariri believes he’ll be able to learn a lot about Ross, about himself, about all of us. As a result, someday he may be able to read your DNA and determine your innate level of anxiety, your propensity for drinking, and a range of other psychological traits.

You can read the rest here.

[PS–You can get more neurological goodness in my two ebooks, Brain Cuttings and More Brain Cuttings.]

Originally published April 18, 2012. Copyright 2012 Carl Zimmer.

Yesterday my Fresh Air interview was broadcast. You can listen to it here. I’ve been lots of emails with follow-up questions, and it occurred to me that I really ought to gather up some links to more information about the topics I discussed.

If I haven’t addressed a question you had listening to the show, leave a comment to this post and I’ll add a link.

Continue reading “Fresh Air interview: links to information on viruses, antivirals, the microbiome, and more” →

As I blogged yesterday, I have a story in the New York Times today about some scientists who are calling for a reformation of science, pointing to troubling indicators such as the rise in retractions of scientific papers.

As any sane journalist would do, I consulted the fantastic Retraction Watch, written by Adam Marcus (left) and Ivan Oransky, while working on my own piece. I also called Oransky for his thoughts on the argument I was describing, championed by, among others, Ferric Fang of the University of Washington and Arturo Casadevall of Albert Einstein College of Medicine.

Continue reading “Retraction Watch in the Boston Globe: Make Science More Transparent” →

In tomorrow’s New York Times, I’ve got a long story about a growing sense among scientists that science itself is getting dysfunctional. For them, the clearest sign of this dysfunction is the growing rate of retractions of scientific papers, either due to errors or due to misconduct. But retractions represent just the most obvious symptom of deep institutional problems with how science is done these days–how projects get funded, how scientists find jobs, and how they keep labs up and running.

Along with the main story, I also wrote a sidebar about how hard it is to hear from the scientists who write retracted papers. I also spoke on the latest Timescast video, which I’ve embedded below. I show up with Arturo Casadevall at about 4:30. There are also lots of links in my story to the original papers. And if you don’t already read it, be sure to check out the blog Retraction Watch, which has been digging deep into the retraction story for years now.

Originally published April 16, 2012. Copyright 2012 Carl Zimmer.

Recently I talked with Dave Davies, guest host on Fresh Air, about viruses and other things invisible. Our conversation airs tomorrow (Tuesday 4/17) on National Public Radio. More details can be found on the program’s web site.

Originally published April 16, 2012. Copyright 2012 Carl Zimmer.