Congratulations to Elizabeth Blackburn, Carol Greider, and Jack Szostak, who just won the Nobel Prize in Physiology or Medicine this morning. They won for their discovery of telomeres, the caps on the ends of chromosomes that keep them from degrading and ward off aging. The Nobel site has posted some useful information about why this was such a profound discovery.

Originally published October 5, 2009. Copyright 2009 Carl Zimmer.

Meet Ardipithecus.

This introduction has been a long time coming. Some 4.4 million years ago, a hominid now known as Ardipithecus ramidus lived in what were then forests in Ethiopia. Fifteen years ago, Tim White of Berkeley and a team of Ethiopian and American scientists published the first account of Ardipithecus, which they had just discovered. But it was just a preliminary report, and White promised more details later, once he and his colleagues had carefully prepared and analyzed all the fossils they had unearthed. “Later,” it turned out, meant 15 years. Continue reading “Ardipithecus: We Meet At Last”

I had a sudden drop in blood pressure when I checked out the new issue of Nature today. Evolutionary biologist Laurence Hurst wrote a two-book review: Richard Dawkins’s The Greatest Show on Earth, and my own The Tangled Bank. I revived when I saw that my book held up under Hurst’s comparison: “The book is billed as the first textbook on evolution for the general reader, and in that framework, it excels.”

Continue reading “Nature: The Tangled Bank “Excels””

Three years ago, I wrote a series of blog posts about how scientists at the University of Oregon reconstructed the 450-million-year history of a protein. You can read the posts here, here, and here. What was particularly elegant about the study was how the scientists recreated the ancestral protein as it existed over 400 million years ago, to see how it functioned. Then they pinpointed the mutations that transformed the protein, shifting it from an old function to a new one.

Recently, the scientists tried to run their experiment backwards. They tried to turn the new protein back into the old one. And they failed. In that failure, they’ve discovered something important. They argue that when it comes to evolution, you can’t go home again.

In today’s issue of the New York Times, I describe this new research, which was recently published in Nature. (Check out the web page of the lead author, Joseph Thornton, for pdf’s of all his papers on this paleoprotein project.)

Originally published September 29, 2009. Copyright 2009 Carl Zimmer.