The New York Times, February 11, 2021

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In recent years, scientists have figured out how to grow blobs of hundreds of thousands of live human neurons that look — and act — something like a brain.

These so-called brain organoids have been used to study how brains develop into layers, how they begin to spontaneously make electrical waves and even how that development might change in zero gravity. Now researchers are using these pea-size clusters to explore our evolutionary past.

In a study published on Thursday, a team of scientists describe how a gene likely carried by Neanderthals and our other ancient cousins triggered striking changes in the anatomy and function of brain organoids.

Continue reading “Tiny Blobs of Brain Cells Could Reveal How Your Mind Differs From a Neanderthal’s”

The New York Times, February 9, 2021

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The invention of Covid-19 vaccines will be remembered as a milestone in the history of medicine, creating in a matter of months what had before taken up to a decade. But Dr. Kayvon Modjarrad, the director of Emerging Infectious Diseases Branch at Walter Reed Army Institute of Research in Silver Spring, Md., isn’t satisfied.

“That’s not fast enough,” he said. More than 2.3 million people around the world have died, and many countries will not have full access to the vaccines for another year or two: “Fast — truly fast — is having it there on day one.”

Continue reading “Could a Single Vaccine Work Against All Coronaviruses?”

The New York Times, February 7, 2021

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A more contagious variant of the coronavirus first found in Britain is spreading rapidly in the United States, doubling roughly every 10 days, according to a new study.

Analyzing half a million coronavirus tests and hundreds of genomes, a team of researchers predicted that in a month this variant could become predominant in the United States, potentially bringing a surge of new cases and increased risk of death.

The new research offers the first nationwide look at the history of the variant, known as B.1.1.7, since it arrived in the United States in late 2020. Last month, the Centers for Disease Control and Prevention warned that B.1.1.7 could become predominant by March if it behaved the way it did in Britain. The new study confirms that projected path.

“Nothing in this paper is surprising, but people need to see it,” said Kristian Andersen, a co-author of the study and a virologist at the Scripps Research Institute in La Jolla, Calif. “We should probably prepare for this being the predominant lineage in most places in the United States by March.”

Continue reading “Virus Variant First Found in Britain Now Spreading Rapidly in U.S.”

The New York Times, February 5, 2021 (with Isabel Kershner)

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In the most extensive real-world test so far, Israel has demonstrated that a robust coronavirus vaccination program can have a quick and powerful impact, showing the world a plausible way out of the pandemic.

Cases of Covid-19 and hospitalizations dropped dramatically among people who were vaccinated within just a few weeks, according to new studies in Israel, where a rapid vaccine rollout has made it a kind of test laboratory for the world. And early data suggests that the vaccines are working nearly as well in practice as they did in clinical trials.

“We say with caution, the magic has started,” tweeted Eran Segal, a quantitative biologist at the Weizmann Institute of Science and co-author of a new study on the vaccine’s impact in Israel.

Continue reading “Israel’s Vaccination Results Point a Way Out of Virus Pandemic”