In March, I wrote a post on some tantalizing new findings about the secrets of human evolution lurking in our genome. In brief, researchers at the University of Pennsylvania studied a gene called MYH16 that helps build jaw muscles in primates. In our own lineage, the gene has mutated and is no longer active in jaw muscles. Perhaps not coincidentally, we have much smaller, weaker jaws than other apes. The researchers estimated that the gene shut down around 2.4 million years ago–right around the time when hominid brains began to expand. They suggested that shrinking jaw muscles opened up room in the hominid head for a larger brain.

Continue reading “Biting the Dust” →

Congratulations to Linda Buck and Richard Axel for winning the Nobel Prize for Medicine today. They won for their pioneering work on the 600 or so receptors that we use to smell. As is so often the case these days, the research that wins people the Nobel for Medicine also reveals a lot about our evolution. This February, for example, Buck published a paper in the Proceedings of the National Academy of Sciences, in which she and her colleagues charted the evolutionary history of human olfactory receptors.

Continue reading “Nobel and Darwin” →

Every now and then you come across a scientific hypothesis that is so elegant and powerful in its ability to explain that it just feels right. Yet that doesn’t automatically make it right. Even when an elegant hypothesis gets support from experiments, it’s not time to declare victory. This is especially true in biology, where causes and effects are all gloriously tangled up with one another. It can take a long time to undo the tangle, and hacking away at it, Gordian-style, won’t help get to the answer any faster.

Continue reading “A Puzzle for the Autumnal Equinox” →