The New York Times, August 29, 2019

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SAN DIEGO — Two hundred and fifty miles over Alysson Muotri’s head, a thousand tiny spheres of brain cells were sailing through space.

The clusters, called brain organoids, had been grown a few weeks earlier in the biologist’s lab here at the University of California, San Diego. He and his colleagues altered human skin cells into stem cells, then coaxed them to develop as brain cells do in an embryo.

The organoids grew into balls about the size of a pinhead, each containing hundreds of thousands of cells in a variety of types, each type producing the same chemicals and electrical signals as those cells do in our own brains.

Continue reading “Organoids Are Not Brains. How Are They Making Brain Waves?” →

The New York Times, August 22, 2019

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A previously unknown outbreak of the Zika virus swept across Cuba in 2017, a year after the global health emergency was declared over, scientists reported on Thursday.

Until now, the Pan American Health Organization had no record of any Zika infection in Cuba in 2017, much less an outbreak. Following inquiries by The New York Times about the new study, published in the journal Cell, officials acknowledged that they had failed to tally 1,384 cases reported by Cuban officials that year.

That figure is a sharp increase over the 187 cases confirmed in 2016 and is “in line with the estimates for 2017 from our own study,” said Kristian Andersen, an infectious disease researcher at Scripps Research Translational Institute in La Jolla, Calif., and a co-author of the new study.

Continue reading “Zika Was Soaring Across Cuba. Few Outside the Country Knew.” →

The New York Times, August 8, 2019

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Scientists have discovered what is by far the oldest evidence of human occupation at extreme altitudes: a rock shelter strewn with bones, tools and hearths 11,000 feet above sea level. People lived at the site, in the mountains of Ethiopia, as long as 47,000 years ago.

The research, reported on Thursday in the journal Science, contradicts the long-held view that high elevations were the last places on Earth settled by humans.

That notion was based more on assumptions than hard evidence, it now appears. In East Africa, paleoanthropologists have long focused their attention on the Rift Valley and other archaeological sites at lower elevations.

Continue reading “In the Ethiopian Mountains, Ancient Humans Were Living the High Life” →

The New York Times, July 18, 2019

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In a laboratory at the Stanford University School of Medicine, the mice are seeing things. And it’s not because they’ve been given drugs.

With new laser technology, scientists have triggered specific hallucinations in mice by switching on a few neurons with beams of light. The researchers reported the results on Thursday in the journal Science.

The technique promises to provide clues to how the billions of neurons in the brain make sense of the environment. Eventually the research also may lead to new treatments for psychological disorders, including uncontrollable hallucinations.

Continue reading “Why Are These Mice Hallucinating? Scientists Are in Their Heads” →