The New York Times, December 15, 2021

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At a World Health Organization meeting on Wednesday, scientists offered some encouraging findings about immunity against the fast-spreading Omicron variant of the coronavirus. Several laboratory studies suggest that so-called T cells in vaccinated people can put up a strong defense against the variant, which could help prevent severe disease, hospitalization and death.

The findings are a welcome departure from a torrent of worrying new data about Omicron. The variant’s mutations enable it to evade many of the antibodies produced either by vaccination or infection with previous variants. But antibodies are not the only important player in a person’s immune response to the virus.

Continue reading “Vaccines will likely protect against severe disease from Omicron, new lab studies suggest.”

The New York Times, December 15, 2021 (with Rebecca Robbins)

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Sanofi, the French pharmaceutical company, said on Wednesday that its once highly anticipated Covid vaccine produced strong immune responses in vaccinated volunteers who received a single dose of the shot as a booster.

The data suggest that the shot, which is still in development and not authorized anywhere in the world, could eventually be used in booster campaigns after it failed to fulfill initial expectations that it would become one of the most important weapons in the fight against the virus. Still, Sanofi has yet to finish a key clinical trial that it said would need to generate results before regulators around the world consider authorizing the shot.

Continue reading “Sanofi’s long-delayed vaccine showed promise as a booster.”

The New York Times, December 14, 2021 (with Rebecca Robbins)

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Pfizer announced on Tuesday that its Covid pill was found to stave off severe disease in a key clinical trial and that it is likely to work against the highly mutated Omicron variant of the virus. The results underscore the promise of the treatment, which health officials and doctors are counting on, to ease the burden on hospitals as the United States braces for a mounting fourth wave of the pandemic.

If the Food and Drug Administration authorizes the drug, which could happen within days, then patients might begin receiving it by the end of the year. Although supply will be limited at first, public health experts are hopeful that the pills might curb the worst outcomes from the disease, no matter the variant.

Continue reading “Pfizer’s Covid Pill Works Well, Company Confirms in Final Analysis”

The New York Times, December 13, 2021 (with Emily Anthes)

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Public health authorities in Denmark and Norway on Monday released grim projections for the coming wave of the Omicron coronavirus variant, predicting that it will dominate both countries in a matter of days. Although scientists don’t yet know how often the variant causes severe disease, they say its rapid rate of spread will lead to an explosion of cases and could potentially increase pressure on hospitals, even if it proves to be mild.

The reports follow similarly worrisome findings from England released over the weekend, although researchers caution that the trend could change as the variant comes into clearer view. It’s not yet certain how often Omicron infections will send people to the hospital, or how many hospitalized patients are likely to die. And while Omicron can partly evade immune defenses, researchers have yet to determine how well vaccinations and previous infections will protect people against severe disease.

Continue reading “Denmark and Norway Predict Drastic Spike in Omicron Cases”

The New York Times, December 7, 2021 (with Benjamin Mueller)

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A report out of South Africa offered a first glimpse at how vaccinated people might fare against the fast-spreading Omicron variant of the coronavirus.

Laboratory experiments found that Omicron seems to dull the power of the Pfizer-BioNTech vaccine, but also hinted that people who have received a booster shot might be better protected.

Continue reading “Pfizer’s vaccine provides some protection against Omicron, a lab study suggests.”