The more you think about sickness and health, the trickier it gets to draw a clean line between them. We tend to think of ourselves as being prepared by nature for a good life. If we can just keep bacteria and viruses from killing us, and avoid walking into open elevator shafts, we’ll live a long, healthy life.

But we are actually the products of evolution, and evolution can’t give us perfect health. It has endowed us with powerful immune systems, thank you very much. And it has endowed us with quick reflexes that can, in some cases, keep us out of open elevator shafts. But evolution doesn’t automatically march to perfection. It stops short, leaving us with grave imperfections.

Continue reading “Why Do We Get Allergies?”

Mosaic, April 6, 2015

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For me, it was hornets.

One summer afternoon when I was 12, I ran into an overgrown field near a friend’s house and kicked a hornet nest the size of a football. An angry squadron of insects clamped onto my leg; their stings felt like scorching needles. I swatted the hornets away and ran for help, but within minutes I realised something else was happening. A constellation of pink stars had appeared around the stings. The hives swelled, and new ones began appearing farther up my legs. I was having an allergic reaction.

Continue reading “Why do we have allergies?”

The New York Times, April 2, 2015

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Some muscles get all the glory. Bodybuilders show off their swollen triceps; sprinters flash their sharp-edged calves. But deep inside all of us, a sheet of muscle does heroic work in obscurity.

In order to breathe in, we must flatten the dome-shaped diaphragm; to breath out, we let it relax again. The diaphragm delivers oxygen to us a dozen times or more each minute, a half-billion times during an 80-year life.

“We are completely dependent on the diaphragm,” said Gabrielle Kardon, a biologist at the University of Utah. “But we take it for granted every moment we’re breathing.”

Continue reading “Behind Each Breath, an Underappreciated Muscle”

Today, Phenomena gains a phenomenal new member: Maryn McKenna. If you’ve read her books such as Superbug or kept up with her blog of the same name, you know that nobody does a better job of analyzing the threats we face from infectious diseases. To celebrate the launch of “Germination,” her blog here at Phenomena, I asked Maryn some questions about how she got here, and where she’s headed.

Continue reading “Please Welcome Maryn McKenna to Phenomena!”

The New York Times, March 25, 2015

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Scientists in Iceland have produced an unprecedented snapshot of a nation’s genetic makeup, discovering a host of previously unknown gene mutations that may play roles in ailments as diverse as Alzheimer’s disease, heart disease and gallstones.

“This is amazing work, there’s no question about it,” said Daniel G. MacArthur, a geneticist at Massachusetts General Hospital who was not involved in the research. “They’ve now managed to get more genetic data on a much larger chunk of the population than in any other country in the world.”

Continue reading “In Iceland’s DNA, New Clues to Disease-Causing Genes”