STAT, January 18, 2016

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To anyone who follows science, President Barack Obama’s announcement of a “moonshot” to cure cancer last week brought on a strong sense of déjà vu. It was, in fact, the third time in less than three years that he has launched a high-profile effort to solve a complex biomedical problem.

A year ago, in his 2015 State of the Union address, Obama announced the Precision Medicine Initiative, which is intended to usher in what he called “a new era of medicine — one that delivers the right treatment at the right time.”

And in an April 2013 speech at the White House, Obama unveiled the BRAIN Initiative, which he described as “the next great American project,” designed to help figure out how the brain works.

Continue reading “Obama’s big bet on science: It’s about far more than a cancer ‘moonshot’”

The New York Times, January 14, 2016

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Loose pieces of DNA course through our veins. As cells in our body die, they cast off fragments of genes, some of which end up in the bloodstream, saliva and urine.

Cell-free DNA is like a message in a bottle, delivering secrets about what’s happening inside our bodies. Pregnant women, for example, carry cell-free DNA from their fetuses. A test that analyzes fetal DNA has proved to be more accurate in screening for Down syndrome than standard blood tests.

In 2012, Jay Shendure, a geneticist at the University of Washington, and his colleagues were able to reconstruct the entire genome of a fetus from cell-free DNA in a pregnant woman’s saliva.

Continue reading “Searching for Cancer Maps in Free-Floating DNA”

The New York Times, January 12, 2016

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The Fish and Wildlife Service is barring the door against 201 species of salamanders, making it illegal to import them or move them across state lines, the agency  announced on Tuesday. Scientists hope the ban will help prevent a devastating outbreak from driving native salamander species extinct.

In 2013, scientists in the Netherlands discovered a species of fungus infecting native fire salamanders. Later research revealed that the fungus, called Batrachochytrium salamandrivorans, or Bsal, was carried by Asian salamanders that were imported into Europe as pets. While the fungus was harmless to the Asian amphibians, it was lethal to the Dutch ones.

Continue reading “U.S. Restricts Movement of Salamanders, for Their Own Good”

The New York Times, January 7, 2016

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Narwhals and newts, eagles and eagle rays — the diversity of animal forms never ceases to amaze. At the root of this spectacular diversity is the fact that all animals are made up of many cells — in our case, about 37 trillion of them. As an animal develops from a fertilized egg, its cells may diversify into a seemingly limitless range of types and tissues, from tusks to feathers to brains.

The transition from our single-celled ancestors to the first multicellular animals occurred about 800 million years ago, but scientists aren’t sure how it happened. In a study published in the journal eLife, a team of researchers tackles this mystery in a new way.

Continue reading “Genetic Flip Helped Organisms Go From One Cell to Many”

STAT, January 7, 2016

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In 1991, a German couple hiking in the Alps came across the body of a middle-aged man lying face down in a snowfield. It took days for a recovery team to hack him out of the ice and haul him by helicopter and truck to a lab in Austria. There, scientists determined the man had died 5,300 years ago.

Ötzi, as the man was nicknamed (after the nearby Ötztal Valley), has kept scientists very busy for the past 24 years. They’ve even built an entire research center — the Institute for Mummies and the Iceman in Bolzano, Italy — to house Ötzi and study him. They’ve slowly extracted one clue after another about how Ötzi died and, more importantly, how he lived.

Continue reading “Scientists unearth bacteria from stomach of 5,300-year-old iceman”